A needle retractable-type safe self-destructing syringe comprising a barrel body (1). An inner needle base body (3) is arranged within a barrel neck (2) at an end part of the barrel body (1). The barrel neck (2) and the inner needle base body (3) match with each other and form therebetween a flexible cushioning stopper engaging mechanism. An asymmetric retracting-locking piece having a flexibility feature is arranged at an end part of a syringe plunger (5). The asymmetric retracting-locking piece is a plastic barb body (12) and is formed with the plunger (8) in a single mold-forming. The asymmetric structure and the flexibility feature implement engagement with and locking onto an inner sleeve-type retracting-locking component (4) in a cavity of a needle base. In a stress environment of an asymmetric force, the needle base deflects to a side after being retracted into the barrel body (1), while an injection needle therefore swings in the direction of a nearly 45 degree angle towards a side of the inner wall of the barrel body (1) and is locked by the barrel neck (2). This prevents the injection needle and the needle base from being pushed out of the barrel neck (2) again, thus effectively preventing secondary injury and implementing safe self-destruction of the syringe.La présente invention concerne une seringue à autodestruction sûre à aiguille remplaçable de type rétractable comprend un corps de cylindre (1). Un corps de base (3) daiguille intérieur est disposé à lintérieur dun col de cylindre (2) au niveau dune partie dextrémité du corps de cylindre (1). Le col de cylindre (2) et le corps de base (3) daiguille intérieur correspondent lun avec lautre et forment entre eux un mécanisme de mise en prise darrêt de rembourrage souple. Une pièce de verrouillage-rétraction asymétrique ayant une caractéristique de souplesse flexibilité caractéristique est agencée au niveau dune partie dextrémité dun piston de seringue (5). La pièce de verrouillage-rétraction asymétrique e
