Karen Julie Gehl,Stine Krog Frandsen,Jens Ole Eriksen,Hanne Margrethe Gissel Hyldkrog,Pernille Højman Jensen
申请号：
US14367439
公开号：
US09943599B2
申请日:
2012.12.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present inventors have shown that electroporation with calcium ions are efficient on cutaneous and subcutaneous nodules. In particular the present inventors here disclose that a solution comprising calcium ions (Ca2+) with a concentration of at least 0.1 M is extremely useful in a method of treating a neoplasm, such as cancer with means for causing transient permeabilization of the cell membranes of at least part of the neoplasm before, during and/or after administration of said solution, wherein said solution is administered with a ratio of 0.2 to 0.8 of the volume of said part of the neoplasm.
