RAMMENSEE, HANS-GEORG, PROF.DR.,STEVANOVIC, STEFAN, PROF. DR.,GOUTTEFANGES, CÉCILE, DR.
申请号:
DK08008944
公开号:
DK2119726T3
申请日:
2008.05.14
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
The present invention relates to peptides, nucleic acids, and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.