STEVANOVIC, STEFAN,GOUTTEFANGES, CECILE,RAMMENSEE, HANS-GOERG,WEINSCHENK, TONI,LEWANDROWSKI, PETER
申请号:
NZ58860509
公开号:
NZ588605A
申请日:
2009.05.14
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are peptides, nucleic acids, and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.