THE PRESENT INVENTION PROVIDES A CYCLIC AMIDE DERIVATIVE USEFUL AS A DRUG FOR TREATING THROMBOSIS, WHICH IS REPRESENTED BY THE FORMULA (Ι): WHEREIN R¹ REPRESENTS AN OPTIONALLY SUBSTITUTED CYCLIC HYDROCARBON GROUP OR AN OPTIONALLY SUBSTITUTED HETEROCYCLIC GROUP, W REPRESENTS A BOND OR AN OPTIONALLY SUBSTITUTED DIVALENT CHAIN HYDROCARBON GROUP, A REPRESENTS 0, 1, OR 2, X¹ REPRESENTS AN OPTIONALLY SUBSTITUTED LOWER ALKYLENE OR AN OPTIONALLY SUBSTITUTED LOWER ALKENYLENE, Y¹ REPRESENTS - C(O)-, -S(O)- OR -S(0)₂-, A REPRESENTS A PIPERAZINE RING WHICH MAY BE FURTHER SUBSTITUTED OR A PIPERIDINE RING WHICH MAY BE FURTHER SUBSTITUTED, X² REPRESENTS A BOND OR AN OPTIONALLY SUBSTITUTED LOWER ALKYLENE, Y² REPRESENTS -C(O)-, -S(O)-, -S(O)₂- OR-C(=NR⁷)-, X³ REPRESENTS AN OPTIONALLY SUBSTITUTED C₁-₄ ALKYLENE OR AN OPTIONALLY SUBSTITUTED C₂-₄ ALKENYLENE, Z³ REPRESENTS -N(R⁴) ,-O- OR A BOND, Z¹ REPRESENTS -C(R²)(R²’ ) - ,-N(R²)- ETC., AND Z² REPRESENTS - C(R³) (R³)-, -N(R³)-, ETC., OR A SALT THEREOF.
