Andrew Simon Bell,Edward William Tate,Robin John Leatherbarrow,Jennie Ann Hutton,James Antony Brannigan
申请号：
US15739166
公开号：
US20180370974A1
申请日:
2016.06.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This invention provides compounds of formula (I) and salts thereof, which have activity as inhibitors of N-myristoyl transferase (NMT). The invention also relates to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of N-myristoyl transferase provides a therapeutic or prophylactic effect, including protozoan infections (such as malaria and leishmaniasis), viral infections (such as human rhinovirus and HIV), and hyperproliferative disorders (such as B-cell lymphoma).
