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噴霧凝固工程の適用下での中間粉末製剤および最終固体剤形の製造方法
专利权人:
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング
发明人:
フォール・アン,ヴォールスポエルス・ヨディ・フィルミン・マルセリネ,メルテンス・ロエル・ヨス・エム,キエケンス・フィリップ・レネ・イレナ
申请号:
JP2011507837
公开号:
JP5674641B2
申请日:
2009.05.08
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The present invention is a liquid form at ambient temperature, in particular having a viscous liquid consistency (e.g., such as oil) or at least one first component having a waxy consistency at ambient temperatures, in particular, solid at ambient temperature or semisolid providing a component melting begins at a temperature ranging from 15 ° C. to 40 ° C. a range of from a temperature higher than the ambient temperature to a temperature lower than the decomposition temperature of said first component, in particular at ambient range of up to 120 ℃ from a temperature higher than the temperature, more range of specifically from a temperature higher than 40 ℃ to 120 ℃, even more specifically in the range of 50 ℃ ~120 ℃ is also more specifically is At least one of the steps of providing a second component, said second component having a melting point or decomposition temperature of the first component from a temperature higher than the melting range having a melting point or melting range in the range of 55 ° C. to 120 ° C. ranging temperature less than, in particular, to hold the second component stirring and either heating the melting point or temperature to a mixture ranging 120. ° C. from a temperature higher than the melting range of, or a mixture at that temperature Accordingly, at least the forming a homogeneous liquid mixture comprising at least one first component and said at least one second component, the mixture was adapted to hold in its liquid form during its movement 1 by one of the mobile device, refers to a liquid mixture comprising the steps of moving at least one spray congealing apparatus, a step of spray congealing the mixture, the powder obtained in the spray solidification method of producing a powder comprising the step of isolating to. Furthermore, the present invention refers to a method for producing a solid dosage form comprising a powder obtained from the above method.本発明は、周囲温度において液体形態である、特に粘性液体稠度を有する(例えば、油など)か、あるいは周囲温度においてワックス状の稠度を有する少なくとも1
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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