592912 A prostate therapy system 800 comprises an ablation probe 840 adapted to be inserted transurethrally into a prostate lobe of an adult male human subject into tissue parallel to a prostatic urethra region of the subject, and a condensable vapour source operatively connected to the ablation probe 840. The ablation probe 840 is configured to deliver condensable vapour from the condensable vapour source into the prostate to deliver between 100 and 10,000 Joules to the prostate to ablate prostate tissue without ablating tissue of the prostatic urethra.