abstract methods of treating a subject having a cardiovascular disease, selecting a therapy for a subject having a cardiovascular disease, identifying a subject having a cardiovascular disease that will benefit or not benefit from exercise therapy, determining whether a subject having a cardiovascular disease should begin, continue, not begin, discontinue, or avoid exercise therapy, determining whether a subject having a cardiovascular disease should continue, discontinue, or avoid exercise therapy, reducing a risk of an adverse outcome (eg, death) in a subject having a cardiovascular disease, and predicting the efficacy of exercise therapy in a subject having a cardiovascular disease. These methods include determining a level of soluble st2 in a subject. -------------------------------------------------- --------------------------- Translation from abstract patent summary: "Methods of treating cardiovascular disease and preventing the effectiveness of exercise therapy " The present invention relates to methods of treating an individual having a cardiovascular disease, selecting a therapy for a patient with a cardiovascular disease, identifying an individual with a cardiovascular disease who will or will not benefit from therapy. of exercise, determine if an individual with cardiovascular disease should start, continue, not start, discontinue or avoid exercise therapy, determine whether an individual who has cardiovascular disease should continue, discontinue or avoid exercise therapy, reducing the risk of an adverse outcome (eg, death) in an individual who has a cardiovascular disease, and predict the effectiveness of exercise therapy in an individual with a cardiovascular disease. These methods include determining a soluble st2 level in an individual.abstract methods of treating a subject having a cardiovascular disease, selecting a therapy for a subject having a cardiovascular disease, identifying a subject having a cardiovascular disease that will benefit or not