The invention relates to a method and apparatus for generation of two-dimensional images using X-rays, proton tomography, and/or carbon ion tomography to form one or more independent and/or integrated three-dimensional images of a tumor, where the proton and carbon cation beams use common elements of a tumor treatment beam, such as an injector, accelerator, and/or beam transport device. A previously collected image of the tumor and/or a current/real-time image control slice is used in control of a multi-axes and/or a multi-field tumor irradiation system for cancer irradiation.
