Martinez-Grau, Maria Angeles,Hoying, Richard Charles,Briner, Karin,Camp, Anne Marie,Sapmaz, Selma,Allen, John Gordon,Cases-Thomas, Manuel Javier,Rathmell, Richard Edmund,Williams, Andrew Caerwyn,Mazan
申请号:
AU2006287160
公开号:
AU2006287160B2
申请日:
2006.09.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepinesof Formula (I) as selective 5-HT receptor agonists for the treatmentof 5-HT associated disorders including obesity, obsessive/compulsivedisorder, depression, and anxiety: where R is -C≡C-R,-CH=CRR , or -(C-C)alkyl-Aroptionally substituted on the alkyl moiety with 1 to 6 fluoro substituents andother substituents are as defined in the specification.