In accordance with the present invention there is provided a suturing device. The suturing device includes a length of suture that will be delivered to the site of the patent foramen ovale (PFO) and placed through the tissue adjacent the opening to close the PFO. The suture is advanced through the tissue surrounding the opening by a pair of needles that penetrate the tissue adjacent to the opening. The suture can be secured to the tissue through use of a knot, a suture clip or other clip like device to retain the suture in a position such that the PFO is closed.