Qiyong Peter Liu,Karin Hoffmeister,Robert Sackstein
申请号:
US14856179
公开号:
US20160000064A1
申请日:
2015.09.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to methods and compositions for reducing sialidase activity and inhibiting bacterial proliferation of one or more bacteria in a platelet product preparation from one or more donors. In general, the method includes contacting the platelet product preparation with an amount of a sialidase inhibitor, to thereby obtain a sialidase inhibitor-treated platelet product preparation. Sialidase activity is reduced and the proliferation of one or more bacteria is inhibited, as compared to a platelet product preparation not subjected to the sialidase inhibitor treatment.