МЯО Чжэньвэй (US),ЧЭНЬ Ган (US),ЧЖУ Тун (US),КХАСАНОВ Алишер Б. (US),ХУН Юйфын (US),ХУХОЛОВСКИЙ Александр (US),ЧЖАНЬ Хун (US)
申请号：
RU2016134258
公开号：
RU2016134258A
申请日:
2014.10.15
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein. More specifically, the present disclosure attaches a first drug conjugate to a dual Cysteine residue on a targeting protein and a second drug conjugate with a different drug to a Lys residue on the targeting protein.
