PARTON ANDREW HARRY,ALI MEZHER HUSSEIN,BROOKINGS DANIEL CHRISTOPHER,BROWN JULIEN ALISTAIR,FORD DANIEL JAMES,FRANKLIN RICHARD JEREMY,LANGHAM BARRY JOHN,NEUSS JUDI CHARLOTTE,QUINCEY JOANNA RACHEL
申请号:
ZA201301751
公开号:
ZA201301751B
申请日:
2013.03.07
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
Disclosed are a series of quinoline and quinoxaline derivatives comprising a fluorinated ethyl side-chain, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. The compounds are of general formula (I):