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METHODS AND MATERIALS FOR EXPANDING ANTIGEN-SPECIFIC T CELLS IN CULTURE
专利权人:
Mayo Foundation for Medical Education and Research
发明人:
Peter A. Cohen,Sandra J. Gendler,Latha B. Pathangey,Dustin B. McCurry,Jessica E. Gorman,Mary L. Disis
申请号:
US15754216
公开号:
US20180245042A1
申请日:
2016.08.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.
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