Mayo Foundation for Medical Education and Research;University of Washington
发明人:
Peter A. Cohen,Sandra J. Gendler,Latha B. Pathangey,Dustin B. McCurry,Jessica E. Gorman,Mary L. Disis
申请号:
US16848110
公开号:
US20200248140A1
申请日:
2020.04.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells) in culture. For example, methods and materials for performing a polyclonal stimulation step for a particular duration (e.g., from about 1 hour to about 48 hours) to increase the expansion of T cells having a desired antigen specificity are provided.