NOVEL THERAPEUTIC USE FOR TREATING LEUKAEMIA

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专利权人:

SANOFI

发明人:

BOURRIE BERNARD,CASELLAS PIERRE

申请号：

SI200730860

公开号：

SI2107906T1

申请日:

2007.12.27

申请国别(地区):

SI

年份:

2012

代理人:

摘要：

Use of N-[2-(2,1,3-benzothiadiazol-5-ylamino)-6-(2,6 dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N-(1,1-dimethylethyl)-urea (I) and its hydrates, salts or solvates, for the preparation of medicament to treat leukemia and myeloids leukemia, is claimed. ACTIVITY : Cytostatic. The anti-tumor activity of (I) was tested in severe combined immunodeficient mice CB-17. The result showed that (I) exhibited tumor mass reduction of 80%. MECHANISM OF ACTION : None given.

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