ULMANN, MARTIN,WIESLER, GERD,BODENMULLER, ARTHUR,MULLER, MARKUS
申请号：
CA3077268
公开号：
CA3077268A1
申请日:
2018.08.29
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl- (6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)- tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin phenylethylbiguanidin, betaine-methylester and dimethylanninoethanol. The cation is an organic compound with a complementary pharmacological activity.
