ULMANN, Martin,WIESLER, Gerd,BODENMÜLLER, Arthur,MÜLLER, Markus
申请号:
AU2018340007
公开号:
AU2018340007A1
申请日:
2018.08.29
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl- (6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)- tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin phenylethylbiguanidin, betaine-methylester and dimethylanninoethanol. The cation is an organic compound with a complementary pharmacological activity.