POLYPEPTIDE SEQUENCE INVOLVED IN THE MODULATION OF THE IMMUNOSUPPRESIVE EFFECT OF VIRAL PROTEINS

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专利权人:

Martial RENARD

发明人:

Martial RENARD,Marianne Mangeney,Thierry Heidmann

申请号：

US13399208

公开号：

US20120189647A1

申请日:

2012.02.17

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Mutated viral ENV proteins having mutations in the immunosuppressive domain (ISU) of the transmembrane subunit (TM) have decreased immunosuppressive activity with respect to the wild-type ENV protein. Pharmaceutical compositions that include the protein and nucleic acids coding for the protein are also disclosed.

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