Compound, pharmaceutical composition and methods of inhibiting ns3 / ns4 protease activity, treating hepatic fibrosis, enhancing liver function in an individual with hepatitis C infection and compounding methods, administering virus infection inhibitor hepatitis c (hcv) and oral dosage form distribution.
LAWRENCE M. BLATT,LIN PAN,SCOTT SEIWERT,STEVEN W. ANDREWS,PIERRE MARTIN,ANDREAS SCHUMACHER,LEONID BEIGELMAN,JYANWEI LIU,KEVIN CONDROSKI,YUTONG JIANG,ROBERT KAUS,APRIL KENNEDY,TIMOTHY KERCHER,MICHAEL L
申请号：
BRPI0811020
公开号：
BRPI0811020A2
申请日:
2008.05.02
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The embodiments provide macrocyclic compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
