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Use of 4-thio-2-deoxynucleosides
专利权人:
SOUTHERN RESEARCH INSTITUTE
发明人:
JOHN A. SECRIST III,KAMAL N. TIWARI,JOSEPH A. MADDRY
申请号:
BRPI0909840
公开号:
BRPI0909840A2
申请日:
2009.03.12
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Compound represented by the formulae: wherein each R individually is H or aliphatic acyl or aromatic acyl group; X is selected from the group consisting of hydrogen, fluoro, chloro, bromo, iodo, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano, aryl and nitro; pharmaceutically acceptable salts thereof, prodrugs thereof and mixtures thereof are used as inhibitors of orthopoxviruses and for treating patients suffering from an orthopoxvirus infection such as, but not limited to, smallpox, cowpox, monkeypox and camelpox.
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