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SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES FOR USE AS ANTIFUNGAL AGENTS
专利权人:
Stefania Gagliardi;Simone Del Sordo;Federico Mailland;Michela Legora
发明人:
Stefania Gagliardi,Simone Del Sordo,Federico Mailland,Michela Legora
申请号:
US13519439
公开号:
US20120329797A1
申请日:
2010.12.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides secondary 8-hydroxyquinoline-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis. These compounds are active against Candida species such as Candida Albicans and Candida Glabrata.
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