SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES FOR USE AS ANTIFUNGAL AGENTS

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专利权人:

POLICHEM S.A

发明人:

GAGLIARDI, Stefania,DEL SORDO, Simone,MAILLAND, Federico,LEGORA, Michela

申请号：

TN2012000321

公开号：

TN2012000321A1

申请日:

2012.06.22

申请国别(地区):

TN

年份:

2013

代理人:

摘要：

The present invention provides secondary 8-hydroxyquinoiine-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulahopsis Brevicaulis. These compounds are active against Candida species such as Candida Albicans and Candida Glabrata.

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