Quinazoline compounds and reversible, Selective inhibitors of the ubiquitin specific Protease 7； Preparation Process； Pharmaceutical compositions containing them and use in the treatment and / or prevention of diseases such as cancer.

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专利权人:

HYBRIGENICS SA

发明人:

COLLAND, FRÉDÉRIC,GOURDEL, MARIE-EDITH

申请号：

CL2014000511

公开号：

CL2014000511A1

申请日:

2014.02.28

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

The present invention relates to compounds of formula (I) their process of preparation and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiquitin specific proteases, particularly USP7, for treating e.g. cancer, neurodegenerative diseases, inflammatory disorders and viral infections.<；p>；COMPUESTOS DERIVADOS DE QUINAZOLINA, INHIBIDORES SELECTIVOS Y REVERSIBLES DE LA PROTEASA ESPECIFICA DE UBIQUITINA 7； PROCESO DE PREPARACIÓ；N； COMPOSICIONES FARMACÉ；UTICAS, COMBINACIONES QUE LOS CONTIENEN Y SU USO EN EL TRATAMIENTO Y/O LA PREVENCIÓ；N DE ENFERMEDADES TALES COMO CÁ；NCER, ALZHEIMER, PÁ；RKINSON, DIABETES, OSTEOPOROSIS.<；/p>；

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http://www.ckcest.cn/home/