The present invention relates to stem cells obtained by culturing monocytes in the presence of (i) M-CSF and (ii) at least one member selected from the group consisting of ganglioside and water-soluble plant-derived extract, thereby dedifferentiating the monocytes a therapeutic agent for treating damaged cells, tissues or organs a cell drug agent a method of producing stem cells, a culture medium for dedifferentiating monocytes a dedifferentiation inducing agent a cell drug kit a kit for producing dedifferentiated cells and a pharmaceutical composition.