A major object of the present invention is to provide a creamy O/W emulsion composition containing an adenosine phosphate ester, more specifically, to provide a creamy O/W emulsion composition containing an adenosine phosphate ester, which ensures emulsification stability and a superior feel during use. Specifically, the present invention provides a creamy O/W emulsion composition containing the following Components (A) to (F) at the following proportions based on its total amount:(A) not less than 0.1 wt. % of adenosine phosphate ester selected from at least one member selected from the group consisting of cyclic adenosine 3′,5′-monophosphate, adenosine monophosphate, adenosine diphosphate, adenosine triphosphate, and salts thereof；(B) 0.5 to 6 wt. % of polyglycerin fatty acid ester；(C) 0.05 to 0.7 wt. % of acrylic acid-alkyl methacrylate copolymer；(D) 0.5 to 10 wt. % of amphiphilic lipid；(E) 0.5 to 20 wt. % of polyhydric alcohol； and(F) 0.3 to 5 wt. % of self-emulsifiable glycerin fatty acid ester.
