PROBLEM TO BE SOLVED: To provide a solid pharmaceutical preparation composition which stably contains each sucralfate and water-unstable drug.SOLUTION: The invention provides a solid pharmaceutical preparation composition which has (A) a sucralfate-containing phase whose moisture content is 10 mass% or more, (B) a water-unstable drug-containing phase whose moisture content is 10 mass% or less, and (C) a division phase which divides the above (A) phase from the (B) phase, and has a water impermeable material.COPYRIGHT: (C)2015,JPO&INPIT【課題】スクラルファート及び水不安定薬物が、いずれも安定に配合された固形医薬製剤組成物を提供することを目的とする。【解決手段】(A)水分量10質量%以上のスクラルファート含有相、(B)水分量10質量%以下の水不安定薬物含有相、及び(C)上記(A)相と(B)相とを分断し、水不透過性材料を有する分断相を有する固形医薬製剤組成物。【選択図】なし
