CONTROLE TEMPOREL IN VIVO D'ENZYMES DE DEGRADATION DE MATRICE ACTIVABLES

• 收藏
• 分享

专利权人:

HALOZYME; INC.

发明人:

KELLER, GILBERT A.,FROST, GREGORY I.

申请号：

CA2718549

公开号：

CA2718549C

申请日:

2009.03.06

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Methods and combinations are provided for controlling the duration of action,in vivo, of matrix-degradingen-zymes. The methods and combinations permit temporary in- vivo activation ofmatrix-degrading enzymes upon administration tothe extra cellular matrix (or "ECM"). Matrix-degrading enzymes having acontrolled duration of action can be used to treatECM--mediated diseases or disorders characterized by increased deposition oraccumulation of one or more ECM components.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/