IN VIVO TEMPORAL CONTROL OF ACTIVATABLE MATRIX-DEGRADING ENZYMES

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专利权人:

Halozyme; Inc.

发明人:

Keller, Gilbert A.,Frost, Gregory I.

申请号：

AU2013202011

公开号：

AU2013202011A1

申请日:

2013.03.26

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013202011A120130418.pdf#####ABSTRACT Methods and combinations are provided for controlling the duration of action, in vivo, of matrix-degrading enzymes. The methods and combinations permit temporary in-vivo activation of matrix-degrading enzymes upon administration to the extra cellular matrix (or "ECM"). Matrix-degrading enzymes having a controlled duration of action can be used to treat ECM-mediated diseases or disorders characterized by increased deposition or accumulation of one or more ECM components.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/