The theophylline derivative disclosed in the present invention is characterized by having the pharmaceutical functions of osteoporosis. The theophylline derivative protects against bone resorption and inflammatory mediator infiltration.本發明係將茶鹼化合物運用於骨質疏鬆症之醫療功能。含茶鹼之醫藥組合物可預防及治療骨質流失之過程,減少發炎細胞之浸潤。