Refers to a process for producing an Allergen extract comprising: a) contacting a material of natural origin with an extracting Agent to produce a mixture of l\u00ccpidos liquid in Liquid phaseAnd a phase s\u00d2lida waste material of origin (b) subject to a First Stage Separation to isolate the waste from the source material (c) contacting the waste from the source material with an Allergen extract Agent to produce a mixture of allergens in Liquid phaseA solid phase and non allergenic waste (d) to submit to the second stage of Separation to produce an extract of crude allergens (e) remove molecules less than 3.5 kDa (f) to carry out stage e) until the extract of allergens is less than 1000\u00b5s \/ cm to 3 - 5C to obtain an Extract Purified Native Allergen extract (g) acidified to pH 2 - 3 Native allergens.0 and keep the acidified extract 5 - 30 minutes, remove molecules less than 3.5 kDa, Adjust pH to 7.0 - 80 to produce a despigmentado Allergen extract (H) to extract a native Contact Allergens or Allergen extract despigmentado with GLUTARALDEHYDE or formaldehyde (i) to eliminate Child 100kda molecules and (j) to carry out the phase I) until this AUSE Allergen extract Nte of GLUTARALDEHYDE, and obtain a despigmentado Polymerized Allergen extract or Polymerized.It also relates to a Pharmaceutical Composition and to a vaccineSE REFIERE A UN PROCESO PARA PRODUCIR UN EXTRACTO DE ALERGENOS QUE COMPRENDE: A) PONER EN CONTACTO UN MATERIAL DE ORIGEN NATURAL CON UN AGENTE DE EXTRACCION LIQUIDA PARA PRODUCIR UNA MEZCLA DE LÌPIDOS EN FASE LIQUIDA, Y UNA FASE SÒLIDA DE RESIDUOS DEL MATERIAL DE ORIGEN B) SOMETER A UNA PRIMERA ETAPA DE SEPARACION PARA AISLAR LOS RESIDUOS DEL MATERIAL DE ORIGEN C) PONER EN CONTACTO LOS RESIDUOS DEL MATERIAL DE ORIGEN CON UN AGENTE DE EXTRACTO DE ALERGENOS PARA PRODUCIR UNA MEZCLA DE ALERGENOS EN FASE LIQUIDA, Y UNA FASE SOLIDA DE RESIDUOS NO ALERGENICOS D) SOMETER A UNA SEGUNDA ETAPA DE SEPARACION PARA PRODUCIR UN EXTRACTO DE ALERGENOS BRUTO E)