A fixation device (1) for a medical line (L) to a patient is provided. The medical line may be a wire, a tube, an endotracheal tube or similar. The fixation device comprises a support member (3) supporting a retainer (5), the retainer defining an axis (A) and being adapted to retain the medical line extending in axial direction. The retainer comprises an enclosure (25) for radially retaining the line and a clamp (27). The clamp is configured to provide a crimping force around the axis for fixing the line in at least axial direction, preferably also radial direction, relative to the enclosure.