The present disclosure relates to a drug delivery device for dispensing of a liquid medicament, the device comprising:a housing to accommodate a cartridge filled with the medicament and having a piston slidably displaced inside the cartridge along an axial direction and sealing a proximal end of the cartridge,a drive mechanism having a piston rod extending along the axial direction and being at least displaceable from a proximal end position in distal direction to displace the piston in distal direction,at least one distal support facing in proximal direction to axially abut a distally facing support face of the cartridge,wherein an axial distance between the distal support and a distal end of the piston rod when in the proximal end position is smaller than an effective length of the cartridge, which effective length is determined as the axial distance between a proximal face of the piston and the distally facing support face.
