GROSSE HOVEST LUDGER GERMANY,BUHRING HANS JORG GERMANY,HOFMANN MARTIN GERMANY,AULWURM STEFFEN GERMANY,JUNG GRUNDRAM GERMANY
申请号：
IN6084/DELNP/2012
公开号：
IN2012DN06084A
申请日:
2012.07.09
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present invention relates to anti FLT3 antibodies with a modified Fc region comprising the amino acid substitututions 239D and 332E to enhance antibody dependent cell cytotoxicity (ADCC) of these antibodies. The invention further relates to pharmaceutical compositions containing these antibodies nucleic acids encoding these antibodies as well as methods of using such antibodies.
