ANTI-FLT3 ANTIBODIES AND METHODS OF USING THE SAME

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专利权人:

Synimmune GmbH

发明人:

GROSSE-HOVEST Ludger,GROSSE-HOVEST Ludger,BUHRING Hans-Jorg,BUHRING Hans-Jorg,HOFMANN Martin,HOFMANN Martin,AULWURM Steffen,AULWURM Steffen,JUNG Grundram,JUNG Grundram

申请号：

SI201031176

公开号：

SI2516468T1

申请日:

2010.12.23

申请国别(地区):

SI

年份:

2016

代理人:

摘要：

The present invention relates to anti-FLT3 antibodies with a modified Fc region comprising the amino acid substitutions 239D and 332E to enhance antibody-dependent cell cytotoxicity (ADCC) of these antibodies. The invention further relates to pharmaceutical compositions containing these antibodies, nucleic acids encoding these antibodies as well as methods of using such antibodies.

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