The invention discloses a composite bone filler for reconstruction and repair of porous structure with multilayer interpenetrating mesh growth promoting layer.There is a core main structure.A first multilayer interpenetrating net growth promoting layer coated on the surface of the main structure of the core；And a plurality of microporous structures arranged on the main structure of the core；The micropore structure is connected with each other to form an accommodation space in the main structure of the core.A second multi-layer interpenetrating net growth promoting layer is arranged on the containing space.The main structure of the core is composed of lifetime medical ceramics.The first layer and the second layer are composed of biodegradable polymers.本創作揭示一種用於重建修復具有多層次互穿網生長促進層微孔洞結構之複合骨填補物，其中包含有一核主體結構；一包覆於該核主體結構表面的第一多層次互穿網生長促進層；以及複數個設置於核主體結構上的微孔洞結構；其中該微孔洞結構彼此相互通連而在該核主體結構內部形成一容置空間，在該容置空間上設置有一第二多層次互穿網生長促進層，該核主體結構係由一生醫陶瓷所組成；該第一多層次互穿網生長促進層與該第二多層次互穿網生長促進層係由生物可分解高分子所組成。
