EPPSTEIN, Jonathan,ENSCORE, David,TAGLIAFERRI, Frank,TOLIA, Gaurav,CHANG, Shulun,SMITH, Alan,PATEL, Yogi,MCRAE, Stuart
申请号：
AU2013200313
公开号：
AU2013200313A1
申请日:
2013.01.21
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013200313A120130207.pdf#####ABSTRACT Disclosed is a device for causing the transdermal flux of a permeant into a subject via at least one formed pathway through a skin layer of the subject. The device comprises a delivery reservoir comprising: i) a non-biodegradable matrix 5 having a bottom surface and defining a plurality of conduits therein the matrix, at least a portion of the plurality of conduits being in communication with the bottom surface； and ii)an undissolved hydrophilic permeant disposed therein at least a portion of the plurality of conduits of the matrix, wherein the hydrophilic permeant can come in contact with subcutaneous fluid from the subject when the bottom surface of the 10 matrix is positioned in fluid communication with the at least one formed pathway. Also disclosed are systems and methods for causing the transdermal flux of a permeant into a subject via at least one formed pathway through a skin layer of the subject. 15 58
