LAPINA, OLGA, VIKTOROVNA,SHI, BING,WANG, FANG,WOLCKENHAUER, SCOTT, ALAN
申请号:
SG11201609810Y
公开号:
SG11201609810YA
申请日:
2015.06.08
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
Crystalline solid forms of methyl {(2S)-1-[(2S,5S)-2-(9-{2-[(2S,4S)-1-{(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl}-1,11-dihydroisochromeno[4′,3′:6,7]naphtho[1,2-d]imidazol-2-yl)-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamate (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using these crystalline forms.