LAPINA, OLGA VIKTOROVNA,SHI, BING,WANG, FANG,WOLCKENHAUER, SCOTT ALAN
申请号：
CA2951188
公开号：
CA2951188A1
申请日:
2015.06.08
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Crystalline solid forms of methyl {(2S)-1-[(2S,5S)-2-(9-{2-[(2S,4S)-1-{(2R)-2- [(methoxycarbonyl)amino] -2-phenylacetyl} -4-(methoxymethyl)pyrrolidin-2-yl] - 1 H-imidazol-5 - yl} -1, 11 -dihydroisochromeno[4,3:6,7]naphtho[ 1,2-d]imidazol-2-yl)-5-methylpyrrolidin- 1 -yl]-3- methyl-l-oxobutan-2-yl} carbamate (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using these crystalline forms.
