Wenyi Wang,Quan Yu,Xiaowu Liu,John Liuzhong Xu,Zhiqiang Du
申请号:
US16537427
公开号:
US20200024362A1
申请日:
2019.08.09
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are antibodies thereof that bind to coagulation factor XI (FXI) and/or its activated form factor XIa (FXIa), or to fragments of FXI and/or FXIa, and compositions containing the antibodies. Also disclosed are methods of preparing the antibodies and use of the antibodies for treating and/or preventing coagulation associated conditions such as thrombosis and complications or conditions associated with thrombosis.