Discloses a composition comprising (A) a galectin-I-interactive agent selected from the group consisting of an antibody that is immuno-interactive with galectin-I, lactulose, a synthetic analogue of lactulose, a semi-synthetic analogue of lactulose and thiodigalactoside and (8) an immune modulating agent selected from the group consisting of an antigen that corresponds to at least a portion of the target antigen, an antigen-binding molecule that is immuno-interactive with the target antigen and an immune-modulating cell that modulates an immune response to the target antigen, wherein the target antigen is a cancer antigen. Further discloses the use of the composition in the manufacture of a medicament for treating or preventing a disease or condition associated with the presence or aberrant expression of a target antigen.
