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Aqueous insulin preparations containing methionine
专利权人:
SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人:
SCHOETTLE ISABELL,HAGENDORF ANNIKA,FUERST CHRISTIANE,HAUCK GERRIT,SIEFKE-HENZLER VERENA,KAMM WALTER,SCHNIEDERS JULIA
申请号:
NZ59775710
公开号:
NZ597757A
申请日:
2010.07.02
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is an aqueous pharmaceutical formulation comprising an insulin, insulin analog or insulin derivative, or a pharmacologically tolerable salt thereof, and methionine as a stabiliser, wherein hyaluronidase is excluded from the formulation, wherein the insulin analog is as defined in the specification, and wherein the pH of the formulation is at a level of 4.5 or less, and wherein the insulin analog and derivative have the blood sugar-lowering capacity of insulin.
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