A veno-merse/harvester device having a handle portion, a hollow shaft portion, and a cutting portion. A fixed cannula system incorporated in the device improves the hydrostatic pressure, which allows efficient hydro-dissection with less retrograde leak of tumescent fluid and facilitates the separation of the vein from surrounding tissues with less bleeding. The veno-merse/harvester device may incorporate a camera system to allow direct visualization of the side branches to be ligated during a procedure. The self-adjustable cutting tip facilitates the forward advancement of the veno-merse/harvester device safely over a dilated portion of a vein.
