IMIDAZOTHIAZOLD DERIVATIVES WITH PROLINING STRUCTURE

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专利权人:

DAIICHI SANKYO COMPANY; LIMITED

发明人:

UOTO KOUICHI,SUGIMOTO YUUICHI,NAITO HIROYUKI,MIYAZAKI MASAKI,YOSHIDA KEISUKE,AONUMA MASASHI

申请号：

DK10731281

公开号：

DK2380892T3

申请日:

2010.01.15

申请国别(地区):

DK

年份:

2014

代理人:

摘要：

[Problem to be Solved] There is provided a novel compound that inhibits interaction between murine double minute 2 (Mdm2) protein and p53 protein and exhibits anti-tumor activity. [Solution] The present invention provides an imidazothiazole derivative represented by the following formula (1) having various substituents that inhibits interaction between Mdm2 protein and p53 protein and exhibits anti-tumor activity: wherein R 1 R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , Ar 1 , and Ar 2 in formula (1) respectively have the same meanings as defined in the specification.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/