ANIMAL MODELS AND THERAPEUTIC MOLECULES

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专利权人:

GENOME RESEARCH LIMITED

发明人:

Jolyon Nicolas Edouard MARTIN,Allan BRADLEY

申请号：

US16604120

公开号：

US20200056202A1

申请日:

2018.04.10

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates inter alia to a rodent or rodent cell having a genome comprising: i) one or more companion animal IGH V region genes, one or more companion animal D region genes and one or more companion animal J region genes； and (ii) optionally one or more companion animal IGL kappa V region genes and one or more companion animal IGL kappa J region genes； and/or one or more companion animal IGL lambda V region genes and one or more companion animal IGL lambda J region genes, wherein the rodent or rodent cell is capable of expressing the companion animal variable region gene(s) to form an antibody chain and wherein the companion animal species is not a rodent.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/