The present application relates to mucoadhesive nanoform microparticles which comprise a biodegradable polymer and on the surface of which a nanostructure is formed. With the microparticles on which a nanostructure is formed according to the present application, the microparticles bring about an increase in bioavailability of therapeutic drugs with drug delivery carriers of which surface stimulation is minimised and the dwell time in the mucosa is long, and thus not only are the effects of drug therapy enhanced and costs reduced due to a lowered drug dose but also convenience for the patient is enhanced.Linvention concerne des microparticules mucoadhésives à nanoforme qui comprennent un polymère biodégradable et sur la surface desquelles une nanostructure formée. Les microparticules sur lesquelles une nanostructure est formée selon linvention permettent dentraîner une augmentation de la biodisponibilité des médicaments thérapeutiques avec des excipients dadministration de médicament dont la stimulation de surface est réduite et le temps de séjour dans la muqueuse est prolongé. En conséquence, non seulement lefficacité dune thérapie médicamenteuse est améliorée et les coûts sont réduits à cause de la diminution de la dose médicamenteuse mais le confort du patient également amélioré.본원은 생분해성 중합체를 포함하며 그 표면에 나노구조가 형성된 점막부착성 나노형상 마이크로 입자에 관한 것이다. 본원에 따른 나노구조가 형성된 마이크로입자는 점막에서의 거주 시간이 길며 표면자극이 최소화된 약물전달체로 치료 약물의 생체이용률 증가를 가져와 약물치료 효과가 증대되고, 약물 투여량의 감소로 비용저하는 물론 및 환자의 편의성이 증대된다.
