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ANTI-FIBROTIC COMPOUNDS
- 专利权人:
- CERTA THERAPEUTICS PTY LTD.
- 发明人:
- MILLER, Thomas,PAPAIOANNOU, Nikolaos
- 申请号：
- SG11201907139U
- 公开号：
- SG11201907139UA
- 申请日:
- 2018.01.31
- 申请国别(地区):
- SG
- 年份:
- 2019
- 代理人:
- 摘要：
- Single and multi-day oral dosing of 116 to male SD rats at 2, 20, 75 and 350 mg/kg/day » z /day 10 +1 5 25 20 mg/kg/day mg/kg/day ...***0501ng/kg/day 10 IS Time post dose th ) (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 09 August 2018 (09.08.2018) WIPO I PCT o °nolo DID momilitiloiflo oimIE (10) International Publication Number WO 2018/144620 Al (51) International Patent Classification: C07C 235/38 (2006.01) C07D 207/24 (2006.01) A61K 31/167 (2006.01) CO7D 209/46 (2006.01) A61P 17/00 (2006.01) CO7D 211/22 (2006.01) CO7C 235/40 (2006.01) CO7D 211/26 (2006.01) CO7C 237/20 (2006.01) CO7D 211/46 (2006.01) CO7C 255/60 (2006.01) CO7D 211/58 (2006.01) CO7D 205/04 (2006.01) CO7D 213/30 (2006.01) CO7D 207/12 (2006.01) (21) International Application Number: PCT/US2018/016272 (22) International Filing Date: 31 January 2018 (31.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/454,358 03 February 2017 (03.02.2017) US (71) Applicant: SHIRE HUMAN GENETIC THERAPIES, INC. [US/US]； 300 Shire Way, Lexington, MA 02421 (US). (72) Inventors: MILLER, Thomas； 18 Park Avenue, Wake- field, MA 01880 (US). PAPAIOANNOU, Nikolaos； 70 Spiers Road, Newton, MA 02459 (US). (74) Agent: DUFFEY, Matthew, 0.； Wolf, Greenfield & Sacks, P.C., 600 Atlantic Avenue, Boston, MA 02210-2206 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN,
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
