具有激酶抑制劑活性之雜戊環农业专利-农业专业知识服务系统

发明人:: ERMES VANOTTI,厄梅斯　瓦诺堤,厄梅斯　瓦諾堤,MARINA CALDARELLI,马里纳　卡尔达雷利,馬里納　卡爾達雷利,ALESSANDRA CIRLA,亚历山大　瑟拉,亞歷山大　瑟拉,BARBARA FORTE,芭芭拉　弗堤,ANTONELLA ERMOLI,安东尼拉　厄墨里,安東尼拉　厄墨里,MARIA MENICHINCHERI,马丽亚　曼尼齐伽里,馬麗亞　曼尼,厄梅斯瓦诺堤,厄梅斯瓦諾堤,马里纳卡尔达雷利,馬里納卡爾達雷利,亚历山大瑟拉,亞歷山大瑟拉,芭芭拉弗堤,安东尼拉厄墨里,安東尼拉厄墨里,马丽亚曼尼齐伽里,馬麗亞曼尼

摘要：: The present invention provides compounds of the formula (I) :or the pharmaceutically acceptable salts thereof, wherein G, W, R2, R3, R4, R5and R6are as defined in the specification. Further objects of the invention are processes and intermediates for the preparation of the compounds of the formula (I), pharmaceutical compositions comprising them and methods for treating cell proliferative disorders. As a matter of fact, the compounds of the formula (I) are useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.本發明提供式(I)化合物：或其醫藥上可接受之鹽，其中G、W、R2、R3、R4、R5及R6係如說明書之定義。本發明之進一步之目的為製備式(I)化合物用之方法及中間產物、包含該等化合物之醫藥組成物及治療細胞增生病症之方法。實際上，式(I)化合物可用於與蛋白質激酶活性失調相關聯之疾病例如癌症之治療。